Best Homemade Meatloaf with Chili Ketchup Sauce

There’s something deeply nostalgic about a slice of homemade meatloaf with sauce.

It reminds me of cozy Sunday dinners, with the scent of savory herbs and caramelized onions filling the kitchen.

This recipe has become a weeknight staple in my home.

It’s hearty, packed with flavor, and the tangy glaze on top? Absolutely irresistible.

Why I Love This Recipe

I love how this easy homemade meatloaf turns a few simple pantry ingredients into a satisfying meal for the whole family.

The texture is moist and tender, and the balance of ketchup, chili sauce, and brown sugar in the glaze adds just the right touch of sweet and savory.

What You’ll Need (Ingredient Highlights)

Lean ground beef – The base of the meatloaf, hearty and protein-packed.

Breadcrumbs & milk – Create moisture and a tender texture.

Onions & butter – Lightly sautéed to add sweetness and depth.

Eggs – For binding everything together.

Ketchup & chili sauce – For bold flavor in both the meat and the glaze.

Italian seasoning & parsley – Add herby freshness.

Brown sugar (optional) – For a touch of sweetness in the glaze.

Pro Tips Before You Start

Don’t overmix the meat – mix until just combined to avoid a dense loaf.

Let the onions cool before mixing them into the beef.

Use a meat thermometer: internal temp should hit 160°F for doneness.

Let the meatloaf rest before slicing so the juices redistribute.

How to Make Easy Homemade Meatloaf with Sauce

Step 1. Prep the oven and pan

Preheat your oven to 350°F (175°C).

Line a rimmed baking sheet with foil and lightly spray it with cooking spray for easy cleanup.

Step 2. Sauté the onions

In a skillet over medium-low heat, cook the diced onion in butter until softened and translucent.

Remove from heat and let cool.

Step 3. Make the binder

In a large mixing bowl, whisk together the eggs, milk, and breadcrumbs.

Let the mixture sit for about 5–10 minutes until slightly thickened.

Step 4. Combine the meat mixture

Add ground beef, sautéed onions, ketchup (or chili sauce), Italian seasoning, parsley, salt, and pepper.

Gently mix everything together until just combined.

Step 5. Shape the loaf

Form the meat mixture into an 8″x4″ loaf and place it on the prepared baking pan.

Step 6. First bake

Bake the loaf for 40 minutes.

Step 7. Make the glaze

In a small bowl, stir together chili sauce, ketchup, and brown sugar (if using).

After 40 minutes of baking, spoon the sauce over the meatloaf.

Step 8. Finish baking

Return the meatloaf to the oven and bake for an additional 15–30 minutes, or until the internal temperature reaches 160°F.

For a caramelized finish, broil for 1–2 minutes at the end.

Step 9. Rest and serve

Let the meatloaf rest for 10 minutes before slicing.

This helps keep it juicy and flavorful.

What to Serve It With

Mashed potatoes and green beans are my go-to.

You can also try it with roasted carrots, a crisp garden salad, or fluffy dinner rolls.

Variations / Substitutions

Swap the meat: Try ground turkey or pork for a lighter version.

Add cheese: Mix in shredded cheddar for a melty center.

Make it spicy: Add a pinch of cayenne or extra chili flakes to the sauce.

Gluten-free: Use GF breadcrumbs and ensure sauces are gluten-free.

Storage & Leftovers

Leftover meatloaf can be stored in the fridge for up to 4 days.

Reheat slices in the microwave or oven.

You can also freeze individual slices (wrapped well) for up to 3 months – perfect for quick lunches.

FAQs

Can I make this meatloaf ahead of time?
Yes! Assemble it, cover tightly, and refrigerate for up to 24 hours before baking.

Why did my meatloaf fall apart?
This usually happens if there’s not enough binder (egg/breadcrumbs) or if it’s overcooked.

Be sure to follow the ingredient ratios.

Is it okay to use dried parsley instead of fresh?
Absolutely – just use about one-third the amount (2 teaspoons dried).

Can I bake this in a loaf pan instead?
Yes, but the cooking time may be slightly longer.

Just be sure to drain excess fat if needed.

What can I use instead of chili sauce?
You can use all ketchup or even BBQ sauce for a smoky twist.

Can I double the recipe?
Yes! Just divide it into two smaller loaves to ensure even cooking.

Do I have to use brown sugar in the sauce?
Not at all. It’s optional but adds a lovely hint of sweetness.

Final Thoughts

This homemade meatloaf with sauce is exactly what comfort food should be: warm, filling, and full of flavor.

It’s a simple recipe with big results, and one that never fails to bring everyone around the table.