Turkey Cranberry Brie Sandwich – Melty, Sweet, and Savory

There’s something magical about the combination of leftover turkey, tart cranberry sauce, and creamy melted brie.

It’s comforting, festive, and somehow manages to taste better than the holiday dinner itself.

This turkey cranberry brie sandwich is my go-to recipe for using up Thanksgiving or Christmas leftovers—and it never disappoints.

Why You’ll Love This Recipe

Perfect for leftovers – repurpose holiday turkey in the most delicious way

Brie melts like a dream, creating a creamy, indulgent bite

Tart cranberry sauce balances the richness perfectly

Sprouted grain bread adds texture and nutrition

Ready in minutes, whether you grill it or press it

What You’ll Need (Ingredient Highlights)

Cooked sliced turkey breast

Brie cheese, rind removed

Whole berry cranberry sauce

Sprouted grain sandwich bread (or your favorite artisan bread)

Butter or ghee for grilling

Pro Tips Before You Start

Use room temperature brie so it melts faster and evenly

Don’t skip the butter or ghee on the bread—it gives that crisp, golden finish

Slice turkey thinly for even layering and quicker heating

Cranberry sauce should be thick, not runny, for best sandwich structure

How to Make Turkey Cranberry Brie Sandwich

Step 1: Prep the Bread

Lay out two slices of sprouted grain (or any sturdy) sandwich bread.

Spread a thin layer of butter or ghee on the outside of each slice.

This will help create a golden crust once grilled.

Flip the slices over so the unbuttered sides face up.

This is where you’ll layer your ingredients.

Step 2: Layer the Fillings

On one slice of bread, add a generous layer of cranberry sauce.

Spread it to the edges for even flavor.

Top the cranberry sauce with sliced turkey breast.

Make sure the slices lie flat and don’t overstuff—it’s easier to press and grill that way.

Next, add slices of brie on top of the turkey.

Cover with the second slice of bread, buttered side out.

Step 3: Grill or Press

Heat a skillet or grill pan over medium heat, or preheat your panini press if using one.

Carefully place the sandwich onto the hot surface.

Grill for 3–4 minutes per side, pressing down gently with a spatula (or using the press), until the bread is golden and the brie is melted.

If using a skillet, you can place another heavy pan or lid on top to mimic a press effect.

Step 4: Serve and Slice

Remove the sandwich from heat and let it rest for a minute.

This helps the melted brie set slightly and prevents burning your fingers.

Slice in half and serve warm—ideally with chips, salad, or a light soup on the side.

Enjoy the perfect balance of creamy, sweet, and savory in every bite.

What to Serve It With

Kettle chips or sweet potato fries

A light green salad with vinaigrette

Roasted butternut squash soup

Pickled onions or cucumbers for contrast

A cup of hot apple cider for a cozy pairing

Variations / Substitutions

Use rotisserie chicken if you don’t have leftover turkey

Swap brie for goat cheese or sharp white cheddar

Try fig jam or apple butter instead of cranberry sauce

Add baby spinach or arugula for a bit of freshness

Use sourdough or brioche for a richer flavor base

Storage & Leftovers

Best enjoyed immediately after grilling

If you must store, wrap in foil and refrigerate for up to 1 day

Reheat in a toaster oven or skillet to regain crispness

Do not microwave—bread will get soggy and cheese uneven

Extra ingredients (turkey, cranberry, brie) can be prepped and stored separately for fast sandwich assembly

FAQs

Can I make this sandwich without a panini press?
Yes! A skillet works perfectly.

Just press the sandwich down gently with a spatula or place a heavy pan on top.

What kind of cranberry sauce should I use?
Whole berry cranberry sauce works best.

Avoid very runny or overly sweet versions for best results.

Can I freeze the sandwich after grilling?
It’s not recommended.

The texture of brie and cranberry changes when frozen and reheated.

What’s a good brie substitute?
Goat cheese, Camembert, or even mozzarella can work.

Brie gives a uniquely creamy texture, but you can adapt.

Can I make this gluten-free?
Absolutely. Use your favorite gluten-free sandwich bread and follow the same steps.

Is this sandwich good for meal prep?
You can prep all the ingredients in advance, but grill the sandwich fresh when ready to eat for best taste and texture.

Final Thoughts

This turkey cranberry brie sandwich is a small post-holiday luxury.

It’s a warm, melty, flavor-packed way to use up leftovers—and honestly, it’s so good you might just buy turkey and brie just to make it again.

Whether you’re curled up with a blanket and a cup of tea or feeding a family crowd, this sandwich delivers every single time.